Research Publications (note J.K. Strauss and J.K. Strauss-Soukup are Dr. Soukup) * indicates undergraduate research student *Klawuhn, K., *Jansen, J.A., *Souchek, J., Soukup, G.A. and Soukup, J.K. Analysis of Metal Ion-Dependence in glmS Ribozyme Self-Cleavage and Coenzyme Binding. (Submitted) *Renner, D., *Johnson, E., Soukup, G.A. and Soukup, J.K. Proton Hopping Mechanism of the glmS ribozyme. (In preparation) *Renner, D., McDevitt, M., Fei, X., Berkowitz, D., Soukup, G.A. and Soukup, J.K. Glucosamine-6-phosphate ligand analogs act as artificial agonists through targeting of the bacterial glmS riboswitch. (In preparation) *Jansen J.A., *McCarthy T.J., Soukup G.A., and Soukup J.K. “Backbone and nucleobase contacts to glucosamine-6-phosphate in the glmS ribozyme.”  Nature Structural & Molecular Biology 13:  517-523  (2006). *McCarthy, T.J., *Plog, M.A., *Floy, S.A., *Jansen, J.A., Soukup, J.K. & Soukup, G.A. "Ligand requirements for glmS ribozyme self-cleavage." Chemistry & Biology 12: 1221-1226 (2005). Soukup, J.K. and G.A. Soukup.  “Riboswitches exert genetic control through metabolite-induced conformational change.” Current Opinion in Structural Biology 14: 344-349  (2004).    Soukup, J.K., Minakawa, N., Matsuda, A., Strobel, S.A.  "Identification of A-Minor Tertiary Interactions within a Bacterial Group I Intron Active Site by 3-Deazaadenosine Interference Mapping."  Biochemistry  41:  10426-10438  (2002). Schmeing T.M., Seila A.C., Hansen J.L., Freeborn B., Soukup J.K., Scaringe S.A., Strobel S.A., Moore P.B., Steitz T.A.  "A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits."  Nature Structural Biology 9:  225-230  (2002). Strauss-Soukup, J.K. and Strobel, S.A.  Chemical Phylogeny of Group I Introns Based upon Interference Mapping of a Bacterial Ribozyme.  Journal of Molecular Biology 302:  339-358  (2000). Basu, S., Rambo, R.P., Strauss-Soukup, J., Cate, J.H., Ferre-D'Amare, A.R., Strobel, S.A., and Doudna, J.A.  A Specific Monovalent Metal Ion Integral to the A-A Platform of the RNA Tetraloop Receptor.  Nature Structural Biology 5:  986-992  (1998). Strauss-Soukup, J.K., Rodrigues, P. and Maher, L.J.  Effect of Base Composition on DNA Bending by Phosphate Neutralization.  Biophysical Chemistry 72:  297-306  (1998). *Tomky, L., Strauss-Soukup, J.K. and Maher, L.J.  Effects of Phosphate Neutralization on the Shape of the AP-1 Transcription Factor Binding Site in Duplex DNA.  Nucleic Acids Research 26:  2298-2305  (1998). Strauss-Soukup, J.K., and Maher, L.J.  Electrostatic Effects in DNA Bending by GCN4 Mutants.  Biochemistry 37:  1060-1066  (1998). Strauss-Soukup, J.K., and Maher, L.J.  Role of Asymmetric Phosphate Neutralization in DNA Bending by PU.1  Journal of Biological Chemistry 272:  31570-31575  (1997). Strauss-Soukup, J.K. and Maher, L.J.  DNA Bending by GCN4 Mutants Bearing Cationic Residues.  Biochemistry 36:  10026-10032  (1997). Strauss-Soukup, J.K., Vaghefi, M.M., Hogrefe, R.I., and Maher, L.J.  Effects of Neutralization Pattern and Stereochemistry on DNA Bending by Methylphosphonate Substitutions.  Biochemistry 36:  8692-8698  (1997). Strauss, J.K., Roberts, C., Nelson, M.G., Switzer, C., and Maher, L.J.  DNA Bending by Hexamethylene Tethered Ammonium Ions.  Proceedings of the National Academy of Sciences U.S.A. 93:  9515-9520  (1996). Strauss, J.K., Prakash, T.P., Roberts, C., Switzer, C., and Maher, L.J.  DNA Bending by a Phantom Protein.  Chemistry & Biology 3:  671-678  (1996). Strauss, J.K. and Maher, L.J.  DNA Bending by Asymmetric Phosphate Neutralization.  Science 266:  1829-1834  (1994).